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The fecal occult blood test (FOBT) is a diagnostic test to assess for occult blood in the stool. This test has commonly been used for colorectal cancer screening, especially in developed nations. Colon cancer is one of the most prevalent cancers in both men and women worldwide, therefore, early detection is imperative. When used correctly for screening, this testing modality has established associations with decreased morbidity and mortality. Newer screening methods, including the fecal immunochemical test (FIT), have been developed. FIT uses antibodies to discern blood in the stool. These newer modalities have replaced the FOBT for colon cancer screening due to increased specificity, sensitivity, and decreased costs.
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